Methods for efficient production of polyunsaturated fatty acids (PUFA) in Rhodosporidium and Rhodotorula species
US10081821B2 · kind B2 · utility
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17Claims
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Key dates
| Filing date | Aug 21, 2015 |
| Grant date | Sep 25, 2018 |
| Priority date | — |
| Expiry date | Aug 21, 2035 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Y604/01002
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention relates to the field of fungal biotechnology, more particularly to genetic engineering methods for the production of polyunsaturated fatty acids (PUFA) in fungal hosts selected from Rhodosporidium and Rhodotorula genera. The present invention further relates to a modified fungal host cell having reduced native aldehyde dehydrogenase (ALD 1) enzyme activity, and methods for producing omega-3 and omega-6 fatty acids and triacylglycerides, by growing said fungal host cell under suitable conditions.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.