Methylene blue nanoparticle for bioimaging and photodynamic therapy and use thereof
US10086075B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Mar 25, 2015 |
| Grant date | Oct 2, 2018 |
| Priority date | — |
| Expiry date | Jun 15, 2035 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K9/5146
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to a methylene blue nanoparticle for bioimaging and photodynamic therapy, and a use thereof as a cancer therapeutic agent and a contrast agent. The methylene blue nanoparticle of the present invention for use as a topical cancer targeting photo therapeutic agent is composed of only a material of which the composition is clinically used or derived from human bodies, and thus a nanopreparation in which a barrier to clinical entry is low and the possibility of commercialization is very high, exhibits near-infrared fluorescence along with cancer targeting property, capacity of generating singlet oxygen and the like, and thus may be used for both bioimaging diagnosis such as optical imaging, and cancer targeting photodynamic therapy.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.