Patent · US Active

Bifunctional cytotoxic agents

US10086085B2 · kind B2 · utility

2Cited by

9References

13Claims

0Family size

Assignee

PFIZER INC. · US

Inventors

Andreas Maderna · Stony Point, US
Matthew David Doroski · Mystic, US
Zecheng Chen · New City, US
Hud Lawrence Risley · Baltic, US
Jeffrey M. Casavant · Franklin, US
Christopher John O'Donnell · Mystic, US
Alexander Michael Porte · Madison, US
Chakrapani Subramanyam · South Glastonbury, US

Key dates

Filing date	Jan 26, 2015
Grant date	Oct 2, 2018
Priority date	—
Expiry date	Jan 26, 2035

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07K9/003
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Cytotoxic dimers comprising CBI-based and/or CPI-based sub-units, antibody drug conjugates comprising such dimers, and to methods for using the same to treat cancer and other conditions.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.