Patent · US Active

Process for the preparation of halo-substituted benzenes

US10087126B2 · kind B2 · utility

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10Claims

0Family size

Assignee

Syngenta Participations AG · CH

Inventors

Helmars Smits · Chur, CH
Paul Knochel · Marburg, DE
Thomas Klatt · Birkenfeld, DE
Matthias Becker · Gauting, DE

Key dates

Filing date	Oct 8, 2015
Grant date	Oct 2, 2018
Priority date	—
Expiry date	Oct 8, 2035

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07C17/383
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

The invention relates to a process for the preparation of compound of formula (I) wherein R1 is halogen and R2 is halogen or hydrogen; comprising a) reacting the compound of formula (II) in an aprotic organic solvent in the presence of an aprotic polar co-solvent with a magnesium amide base followed by a halogenating agent, to the compound of formula I wherein R1 is halogen and R2 is hydrogen, and b) reacting the compound of formula (I), wherein R1 is chloro and R2 is hydrogen, in an aprotic organic solvent in the presence of an aprotic polar co-solvent with a magnesium amide base followed by a halogenating agent to a compound of formula I, wherein R1 is chloro and R2 is halogen.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.