Necrosis inhibitors
US10092529B2 · kind B2 · utility
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20Claims
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Assignee
Inventors
Key dates
| Filing date | Jun 26, 2017 |
| Grant date | Oct 9, 2018 |
| Priority date | — |
| Expiry date | Jun 26, 2037 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01C19/5747
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention provides amides that inhibit cellular necrosis and/or human receptor interacting protein 1 kinase (RIP1), including corresponding sulfonamides, and pharmaceutically acceptable salts, hydrides and stereoisomers thereof. The compounds are employed in pharmaceutical compositions, and methods of making and use, including treating a person in need thereof with an effective amount of the compound or composition, and detecting a resultant improvement in the person's health or condition.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.