Compositions and methods for inducing conformational changes in cereblon and other E3 ubiquitin ligases
US10092555B2 · kind B2 · utility
5Cited by
58References
7Claims
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Key dates
| Filing date | Jun 26, 2015 |
| Grant date | Oct 9, 2018 |
| Priority date | — |
| Expiry date | Oct 3, 2035 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG16B15/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Provided herein are compositions, therapeutic methods, screening methods, computational methods and biomarkers based upon the elucidation of the interaction among cereblon, its substrates and certain compounds or agents, including small molecules, peptides, and proteins.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.