Controlled-release otic structure modulating and innate immune system modulating compositions and methods for the treatment of otic disorders

US10092580B2 · kind B2 · utility

Assignees

• OTONOMY, INC. · US
• The Regents of the University of California · US

Inventors

• Jay Lichter · Rancho Santa Fe, US
• Benedikt Vollrath · San Diego, US
• Sergio G. Duron · San Diego, US
• Carl Lebel · Malibu, US
• Fabrice Piu · San Diego, US
• Qiang Ye · San Diego, US
• Luis A. Dellamary · San Marcos, US
• Andrew M. Trammel · Olathe, US
• Michael Christopher Scaife · Pittsburgh, US
• Jeffrey P. Harris · Village of La Jolla, US

Key dates

• Filing date: Jul 20, 2009
• Grant date: Oct 9, 2018
• Expiry date: Nov 23, 2030

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P27/16
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Disclosed herein are compositions and methods for the treatment of otic disorders with otic structure modulating compositions administered locally to an individual afflicted with an otic disorder, through direct application of these compositions and compositions onto or via perfusion into the targeted auris structure(s).