Methods for enhancing hematopoietic stem/progenitor cell engraftment
US10092599B2 · kind B2 · utility
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Key dates
| Filing date | May 7, 2015 |
| Grant date | Oct 9, 2018 |
| Priority date | — |
| Expiry date | Jul 29, 2035 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K2035/124
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Described herein are methods for enhancing engraftment of hematopoietic stem and progenitor cells using compounds identified using a zebrafish model of hematopoietic cell engraftment. The compounds can be used to treat hematopoietic stem cells ex vivo prior to transplantation of the cells. Alternatively, the compounds can be administered to an individual undergoing cell transplantation.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.