Newly identified peptides for use in the induction of oral tolerance in young mammals
US10092633B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Dec 16, 2013 |
| Grant date | Oct 9, 2018 |
| Priority date | — |
| Expiry date | Dec 16, 2033 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K2039/577
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention relates to newly identified peptides of that are capable of inducing tolerance to cow's milk, especially to β-lactoglobulin. The peptides may be administered to mammals, especially to young infants who are at risk of allergy to cow's milk proteins, to induce oral tolerance to cow's milk; they may also be administered to children or adults who are allergic to cow's milk to allow “desensitization” towards the allergenic milk proteins, especially β-lactoglobulin, to occur. The peptides may also be used to induce tolerance to goat's and buffalo's milk proteins, especially β-lactoglobulin. The peptides are capable of modulating the mammalian immune response to allergens.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.