High-content fast dissolving film with masking of bitter taste comprising sildenafil as active ingredient
US10092651B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Feb 28, 2013 |
| Grant date | Oct 9, 2018 |
| Priority date | — |
| Expiry date | Feb 28, 2033 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P15/10
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Provided is a fast dissolving film composition comprising a medically active component as an active ingredient, in which the bitter taste of the active ingredient is masked and the fast dissolving film composition has a high content of 50% or higher. More particularly, provided is a pharmaceutical composition which comprises sildenafil or pharmaceutically acceptable salts thereof as an active ingredient, and which comprises a combination of a specific bitter taste masking agent to achieve masking of a bitter taste. Further, provided is a fast dissolving film composition which comprises a combination of a specific plasticizer to mask a bitter taste, and in which the physical properties of the high-content film are excellent.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.