Supramolecular nanofibers and hydrogels based on nucleic acids functionalized with nucleobases
US10093674B2 · kind B2 · utility
Assignee
Inventor
Key dates
| Filing date | Dec 2, 2013 |
| Grant date | Oct 9, 2018 |
| Priority date | — |
| Expiry date | Aug 7, 2034 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07H13/04
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Disclosed are nucleopeptide compounds that include a nucleobase, and an amino acid. Certain compounds further comprise a glycoside. The compounds may self-assemble to form supramolecular hydrogels. Also, the compounds may be used as a platform to examine specific biological functions (e.g., binding to DNA and RNA) of a dynamic supramolecular system that is able to interact with both proteins and nucleic acids. Other uses include: methods of growing cells and methods of delivering a substance to a cell.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.