Beta-lactamase inhibitors

US10093685B2 · kind B2 · utility

Assignee

• VENATORX PHARMACEUTICALS, INC. · US

Inventors

• Christopher J. Burns · Vivonne Bay, AU
• Denis DAIGLE · Street, US
• Bin Liu · Fishers, US
• Daniel McGarry · King of Prussia, US
• Daniel C. Pevear · Downingtown, US
• Robert E. Lee TROUT · Collegeville, US
• Randy W. Jackson · Livingston, US

Key dates

• Filing date: Aug 11, 2017
• Grant date: Oct 9, 2018
• Expiry date: Aug 11, 2037

Classification

• Technology area (CPC —): General

Abstract

Described herein are compounds and compositions that modulate the activity of beta-lactamases. In some embodiments, the compounds described herein inhibit beta-lactamase. In certain embodiments, the compounds described herein are useful in the treatment of bacterial infections.