Patent · US Active

Multispecific GITR-binding fusion proteins and methods of use thereof

US10093742B2 · kind B2 · utility

4Cited by

12References

57Claims

0Family size

Assignee

Inhibrx, Inc. · US

Inventors

John C. Timmer · Village of La Jolla, US
Kyle S. Jones · San Marcos, US
Amir S. Razai · Village of La Jolla, US
Abrahim Hussain · Village of La Jolla, US
Katelyn M. Willis · Village of La Jolla, US
Quinn Deveraux · Village of La Jolla, US
Brendan P. Eckelman · Village of La Jolla, US

Key dates

Filing date	Jul 22, 2016
Grant date	Oct 9, 2018
Priority date	—
Expiry date	Jul 22, 2036

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07K2317/92
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

This disclosure generally provides molecules that specifically engage glucocorticoid-induced TNFR-related protein (GITR), a member of the TNF receptor superfamily (TNFRSF). More specifically, the disclosure relates to multivalent and/or multispecific molecules that bind at least GITR.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.