Self-assembly of therapeutic agent-peptide nanostructures
US10098967B2 · kind B2 · utility
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Key dates
| Filing date | Dec 3, 2013 |
| Grant date | Oct 16, 2018 |
| Priority date | — |
| Expiry date | Jan 25, 2034 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K47/64
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Disclosed are conjugates of hydrophobic drugs linked to protected or unprotected amino acids or peptides. The disclosed conjugates are amphiphilic and can self assemble into nantubes. Nanotubes comprising the conjugates are also described and can have high loading of the drug and protect it from degradation or elimination. The nanotubes are well suited to deliver hydrophobic and unstable drugs to individuals.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.