Lappaconitine aza-cinnamic acid derivatives with anti-tumor activities and a method of preparing the same

US10100036B2 · kind B2 · utility

Assignee

• SHAANXI UNIVERSITY OF SCIENCE AND TECHNOLOGY · CN

Inventors

• Chengyuan Liang · Xi'an, CN
• Minyi Jia · Xi'an, CN
• Xingke Ju · Xi'an, CN
• Lei Tian · Batou, CN
• Danni Tian · Xi'an, CN
• Shunjun Ding · Xi'an, CN

Key dates

• Filing date: Sep 25, 2017
• Grant date: Oct 16, 2018
• Expiry date: Sep 25, 2037

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P35/00
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

A lappaconitine aza-cinnamic acid derivative having the following formula (I): X is C or N, and R1, R2, and R3 are independently H or lower alkyl. A method of preparing the lappaconitine aza-cinnamic acid derivative of formula (I) is also disclosed.