Patent · US Active

Differentiation of pluripotent cells

US10100282B2 · kind B2 · utility

3Cited by

5References

48Claims

0Family size

Assignee

FUJIFILM Cellular Dynamics, Inc. · US

Inventors

Deepika Rajesh · Madison, US
Rachel Lewis · Madison, US

Key dates

Filing date	Feb 1, 2013
Grant date	Oct 16, 2018
Priority date	—
Expiry date	Jan 28, 2034

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12N2506/45
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Provided herein are methods for the in vitro maintenance, expansion, culture, and/or differentiation of pluripotent cells, such as human embryonic stem cells (hESC) or induced pluripotent cells (iPSC), into hematopoietic precursor cells or endothelial cells. The pluripotent cells may be maintained and differentiated under defined conditions; thus, the use of mouse feeder cells or serum is not required in certain embodiments for the differentiation of the pluripotent cells into hematopoietic precursor cells or endothelial cells. The resulting hematopoietic precursor cells may be further differentiated into various myeloid or lymphoid lineages.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.