Evaluating biological material for unassociated virus-size particles with adeno-associated virus epitope
US10101262B2 · kind B2 · utility
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4References
31Claims
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Key dates
| Filing date | Sep 22, 2017 |
| Grant date | Oct 16, 2018 |
| Priority date | — |
| Expiry date | Sep 22, 2037 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2469/10
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A method for evaluating a biological material for unassociated virus-size particles having a particular epitope indicative of an adeno-associated virus viral type or an adenovirus viral type uses a fluorescent antibody stain specific for binding with the epitope and a fluid sample with the virus-size particles and fluorescent antibody stain is subjected to flow cytometry with identification of fluorescent emission detection events indicative of passage through a flow cell of a flow cytometer of unassociated labeled particles of virus size including such a virus-size particle and fluorescent antibody stain.
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