Magnetic sensor based quantitative binding kinetics analysis
US10101299B2 · kind B2 · utility
1Cited by
18References
18Claims
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Key dates
| Filing date | Mar 11, 2011 |
| Grant date | Oct 16, 2018 |
| Priority date | — |
| Expiry date | Dec 29, 2034 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10T436/143333
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Methods for quantitatively determining a binding kinetic parameter of a molecular binding interaction are provided. Aspects of embodiments of the methods include: producing a magnetic sensor device including a magnetic sensor in contact with an assay mixture including a magnetically labeled molecule to produce a detectable molecular binding interaction; obtaining a real-time signal from the magnetic sensor; and quantitatively determining a binding kinetics parameter of the molecular binding interaction from the real-time signal. Also provided are systems and kits configured for use in the methods.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.