Hydrophilic macromers and hydrogels comprising the same

US10101499B2 · kind B2 · utility

Assignee

• Momentive Performance Materials GmbH · US

Inventors

• Anubhav Saxena · Bengaluru, IN
• Monjit Phukan · Bengaluru, IN
• Shreedhar Bhat · Bengaluru, IN
• Kenrick M. Lewis · New York, US
• Senthilkumar Umapathy · Bengaluru, IN

Key dates

• Filing date: Sep 22, 2014
• Grant date: Oct 16, 2018
• Expiry date: Sep 22, 2034

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C08L2201/10
• WIPO field: Macromolecular chemistry, polymers
• WIPO sector: Chemistry

Abstract

A composition, suitable for use in producing hydrogel polymer films from which biomedical devices such as contact lenses can be made, comprising at least one hydrophilic silicone macromer. In one aspect, a hydrophilic silicone macromer is of the Formula 1: X—Si(R1)(R2)O—(Si(R3)(R4)O)a—Si(R5)(R6)—Y  (1) wherein R1, R2, R3 R4, R5 and R6 are independently selected from a monovalent linear, branched, or cyclic radical with 1 to 50 carbon atoms, that can optionally contain a heteroatom or I; I is RL—RP; Y is a free radical polymerization-effective hydrophilic group with the general structure: RL—RP—Z; RL is a linking residue from a non-isomerizable hydrosilylation effective terminal olefin comprising the general structure —CH2—C(RbR7)—(CR8R9)n, the subscript n is selected from integers from 1 to 10; R7, R8, and R9 can be selected from hydrogen and a mono-valent hydrocarbon radical with 1 to 10 carbon atoms that optionally contain a heteroatom; Rb is selected from a monovalent hydrocarbon radical with 1 to 6 carbon atoms; RP is a spacer group comprising a diavelant hydrophilic organic radical with 0 to 100 carbon atoms and optionally contains heteroatoms, and X is a free radical polymeri…