Methods and pharmaceutical compositions for expressing a polynucleotide of interest in the retinal pigment epithelium of a subject
US10105452B2 · kind B2 · utility
2Cited by
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16Claims
0Family size
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Key dates
| Filing date | Dec 5, 2014 |
| Grant date | Oct 23, 2018 |
| Priority date | — |
| Expiry date | Dec 5, 2034 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2750/14171
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to methods and pharmaceutical compositions for expressing a polynucleotide of interest in the retinal pigment epithelium of a subject. In particular, the present invention relates to a method for selectively expressing a polynucleotide of interest in the retinal pigment epithelium in an eye of a subject in need thereof comprising the step of transducing the retinal pigment epithelium with an amount of a rAAV2/5 vector containing the polynucleotide of interest.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.