Patent · US Active

Fluorocoxib A loading into ROS-responsive nanoparticles

US10105455B2 · kind B2 · utility

0Cited by

3References

13Claims

0Family size

Assignee

VANDERBILT UNIVERSITY · US

Inventors

Craig L. Duvall · Nashville, US
Lawrence J. Marnett · Nashville, US
Jashim Uddin · Nashville, US
Thomas A. Werfel · Nashville, US
Mukesh K. Gupta · Nashville, US
Brenda C. Crews · Franklin, US

Key dates

Filing date	Jul 11, 2016
Grant date	Oct 23, 2018
Priority date	—
Expiry date	Jul 11, 2036

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61K49/0082
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Disclosed are compositions that comprise a cyclooxygenase-2-selective therapeutic and/or diagnostic agent having a therapeutic and/or diagnostic agent conjugated to a NSAID drug; and a ROS-responsive nanoparticle. Methods of making and using these compositions for drug encapsulation and delivery are also disclosed.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.