Method for phosgenating compounds containing hydroxyl, thiol, amino and/or formamide groups

US10105675B2 · kind B2 · utility

Assignee

• BAYER HEALTHCARE LLC · DE

Inventors

• Leslaw Mleczko · Bochum, DE
• Aurel Wolf · Wülfrath, DE
• Ralf Schellen · Moers, DE
• Konstantinos METAXAS · Cologne, DE
• Jens Stefan Roggan · Cologne, DE

Key dates

• Filing date: Aug 17, 2015
• Grant date: Oct 23, 2018
• Expiry date: Aug 17, 2035

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07C263/10
• WIPO field: Chemical engineering
• WIPO sector: Chemistry

Abstract

The invention relates to a method particularly for reacting phosgene with compounds that contain hydroxyl, thiol, amino and/or formamide groups, comprising the steps of: (I) providing a reactor which has a first reaction chamber (300, 310, 320, 330, 340, 350) and a second reaction chamber (200, 210, 220, 230, 240, 250, 260), the first and the second reaction chambers being separated from one another by means of a porous carbon membrane (100, 110, 120, 130, 140, 150); (II) providing carbon monoxide and chlorine in the first reaction chamber; and simultaneously (III) providing a compound containing hydroxyl, thiol, amino and/or formamide groups in the second reaction chamber. The porous carbon membrane is configured to catalyze the reaction of carbon monoxide and chlorine to obtain phosgene, and to allow this formed phosgene to pass into the second reaction chamber. The invention also relates to a reactor that is suitable for carrying out the claimed method.