Patent · US Active

Materials and methods for producing cleaved, HIV-1 envelope glycoprotein trimers

US10106583B2 · kind B2 · utility

0Cited by

5References

16Claims

0Family size

Assignee

Cornell University · IT

Inventors

Andre Marozsan · Boston, US
Albert Cupo · Stamford, US
John P. Moore · New York, US

Key dates

Filing date	Mar 9, 2015
Grant date	Oct 23, 2018
Priority date	—
Expiry date	Mar 9, 2035

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12N2740/16134
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Expression vectors and mammalian cell lines containing them are described that enable the recombinant production of HIV-1 envelope proteins, including SOSIP modified gp140 trimers capable of inducing broadly neutralizing antibodies.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.