Human antibody specific to c-Met and preparation method thereof
US10106622B2 · kind B2 · utility
6Cited by
2References
8Claims
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Key dates
| Filing date | Jul 28, 2015 |
| Grant date | Oct 23, 2018 |
| Priority date | — |
| Expiry date | Jul 28, 2035 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2317/92
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Provided are an antibody specifically bound to c-Met (c-Met-specific antibody) or fragments thereof, and more specifically, a fully human antibody having high affinity and specificity to c-Met isolated from human Fv(ScFv) phage library, a polynucleotide encoding the antibody, a recombinant vector containing the polynucleotide, a cell transformed with the recombinant vector, and a method of producing the c-Met-specific antibody by culturing the cell, wherein the c-Met-specific antibody may effectively control activity of c-Met in vivo.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.