Induction of hemogenic endothelium from pluripotent stem cells by forced expression of transcription factors
US10106771B2 · kind B2 · utility
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Key dates
| Filing date | Aug 23, 2017 |
| Grant date | Oct 23, 2018 |
| Priority date | — |
| Expiry date | Aug 23, 2037 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2740/16043
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Described herein are methods and related compositions for inducing differentiation of human pluripotent stem cells (hPSCs) into hemogenic endothelium with pan-myeloid potential or restricted potential, by forced expression in the hPSCs of a combination of transcription factors as described herein.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.