Isolation and use of pluripotent stem cell population from adult neural crest-derived tissues
US10106773B2 · kind B2 · utility
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Key dates
| Filing date | Mar 1, 2013 |
| Grant date | Oct 23, 2018 |
| Priority date | — |
| Expiry date | Apr 13, 2034 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2506/03
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to methods of isolating a substantially homogeneous population of pluripotent stem cells from adult neural crest tissue (e.g., periodontal ligament) as well as pharmaceutical compositions comprising such isolated pluripotent stem cells. Methods of inducing the isolated pluripotent stem cells into specific cell lineages, such as neurogenic and retinogenic lineages, are also described. The isolated pluripotent stem cells find use in various regenerative medicine applications and the treatment of degenerative diseases.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.