Selective targeting of cancer stem cells
US10106778B2 · kind B2 · utility
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21Claims
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Key dates
| Filing date | Nov 8, 2013 |
| Grant date | Oct 23, 2018 |
| Priority date | — |
| Expiry date | Nov 10, 2033 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2501/727
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Aspects of the invention relate to methods and related compositions for preferentially targeting cancer stem cells. In some embodiments, the methods utilize PKC-α/FRA1 pathway inhibitors to target carcinoma cells. Also provided are methods for identifying a candidate compound for selectively inhibiting growth of cancer stem cell, and methods for obtaining cells that have undergone an epithelial to mesenchymal transition.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.