Method to perform limited two dimensional separation of proteins and other biologicals
US10107782B2 · kind B2 · utility
7Cited by
46References
20Claims
0Family size
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Key dates
| Filing date | Jan 23, 2009 |
| Grant date | Oct 23, 2018 |
| Priority date | — |
| Expiry date | May 22, 2029 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N27/44773
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A method and apparatus are provided for performing capillary isoelectric focusing followed by mobilization of the focused zones by induced hydrodynamic flow or chemical mobilization. These two dimensions of separation are integrated with real-time whole-channel electrophoresis detection and automatic sample injection to achieve a separation resolution superior to that obtainable using known orthogonal capillary two dimensional arrangements.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.