Patent · US Active

Method of identifying peptides

US10107820B2 · kind B2 · utility

2Cited by

2References

17Claims

0Family size

Assignee

THE TRUSTEES OF INDIANA UNIVERSITY · US

Inventors

James P. Reilly · Vancouver, US
Liangyi Zhang · Shanghai, CN

Key dates

Filing date	Dec 31, 2010
Grant date	Oct 23, 2018
Priority date	—
Expiry date	Mar 8, 2031

Classification

Technology area (CPC G)Physics
CPC primaryG16B40/00
WIPO fieldMeasurement
WIPO sectorInstruments

Abstract

Methods of identifying polypeptides have been developed using a de novo sequencing technique. Methods use photodissociation and low-energy fragmentation and the spectra of peptide ions obtained therefrom, such as obtained by post-source decay (PSD), have been developed. The methods include photodissociation and the spectra therefrom obtainable from treating ions with predetermined wavelengths of radiation in the vacuum ultraviolet range of the electromagnetic spectrum. The confidence of amino acid assignments based on x-type ions is evaluated by observing complementary y-, v- and w-type ions that provide additional constraints to sequence identification.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.