Anti-tumor compositions and methods
US10111898B2 · kind B2 · utility
1Cited by
4References
20Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jun 15, 2015 |
| Grant date | Oct 30, 2018 |
| Priority date | — |
| Expiry date | Jun 15, 2035 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2310/351
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Disclosed herein are oligonucleotide sequences that generate innate immunity in cells within tumors upon its delivery into tumors. In certain embodiments, these oligonucleotides are specifically delivered into tumors through nanoparticles displaying targeting peptides that confer specific binding of the nanoparticle to receptors on the surface of tumor cells and allow for uptake of the nanoparticle into the tumor cells.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.