Patent · US Active

β-glucan methods and compositions that affect the tumor microenvironment

US10111900B2 · kind B2 · utility

1Cited by

42References

20Claims

0Family size

Assignee

BIOTHERA INC. · US

Inventors

Nandita Bose · Plymouth, US
Keith B. Gorden · Woodbury, US
Anissa SH. CHAN · Arden Hills, US
Steven Leonardo · Rosemount, US
Jeremy Graff · Indianapolis, US
Xiaohong Qiu · Edina, US
Takashi KANGAS · Shoreview, US
Kathryn Fraser · Windom, US
Adria BYKOWSKI JONAS · Eden Prairie, US
Nadine OTTOSON · Lakeville, US
Ross Fulton · Southborough, US

Key dates

Filing date	Dec 21, 2016
Grant date	Oct 30, 2018
Priority date	—
Expiry date	Dec 21, 2036

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12N2502/1114
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

This disclosure relates to the combination of soluble β-glucan and immune suppression-relieving agents that affect the tumor microenvironment. Soluble β-glucan promotes an immunostimulatory environment, which allows enhanced effectiveness of anti-angiogenics, checkpoint inhibitors including non-tumor targeting antibodies.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.