Patent · US Active

Silicon dioxide nanoparticles and the use thereof for vaccination

US10111952B2 · kind B2 · utility

0Cited by

2References

28Claims

0Family size

Assignee

Merck Patent GmbH · DE

Inventors

Markus Weigandt · Mannheim, DE
Andrea Hanefeld · Darmstadt, DE
Armin Kuebelbeck · Bensheim, DE
Gregor Larbig · Gelnhausen, DE

Key dates

Filing date	Oct 6, 2017
Grant date	Oct 30, 2018
Priority date	—
Expiry date	Oct 6, 2037

Classification

Technology area (CPC Y)Emerging Cross-Sectional Technologies
CPC primaryY10T428/2982
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The invention relates to ultrasmall, monodisperse nanoparticles comprising silicon dioxide to the surface of which at least one antigen is attached. The nanoparticles can be used for the immunoprophylaxis or immunotherapy of cancer. The invention also relates to a method for the targeting of antigens at antigen-presenting cells and for the activation of the immune system, where the efficiency of targeting and/or immunoactivation are set via the particle characteristics. The invention also relates to a method for the active and passive immunisation of a mammal.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.