uPAR targeting peptide for use in peroperative optical imaging of invasive cancer
US10111969B2 · kind B2 · utility
3Cited by
1References
3Claims
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Key dates
| Filing date | Sep 3, 2015 |
| Grant date | Oct 30, 2018 |
| Priority date | — |
| Expiry date | Sep 3, 2035 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K49/0034
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
There is provided a novel conjugate that binds to the cell surface receptor uPA (uPAR). The conjugate is based on a fluorescence-labeled peptide useful as a diagnostic probe to the surfaces of cells expressing uPAR. The conjugate is capable of carrying a suitable detectable and imageable label that will allow qualitative detection and also quantitation of uPAR levels in vitro and in vivo. This renders the surgical resection of tumors more optimal.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.