(Cyano-dimethyl-methyl)-isoxazoles and -[1,3,4]thiadiazoles

US10112934B2 · kind B2 · utility

Assignee

• Centrexion Therapeutics Corporation · US

Inventors

• Doris Riether · Biberach an der Riß, DE
• Florian Paul Christian Binder · Maselheim, DE
• Henri Doods · Warthausen, DE
• Stephan Georg Mueller · Warthausen, DE
• Janet Rachel Nicholson · Oberhofen, DE
• Achim Sauer · Ravensburg, DE

Key dates

• Filing date: Apr 19, 2017
• Grant date: Oct 30, 2018
• Expiry date: Apr 19, 2037

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D413/14
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

This invention relates to novel (Cyano-dimethyl-methyl)-isoxazoles and -[1,3,4]thiadiazoles and their use as CB2 cannabinoid receptor agonists, pharmaceutical compositions containing the same, and their use for the treatment of CB2 receptor mediated disorders or conditions.