IL-2 peptide derivatives, and uses thereof for the diagnosis and treatment of an autoimmune disease
US10114018B2 · kind B2 · utility
Inventors
Key dates
| Filing date | Apr 21, 2015 |
| Grant date | Oct 30, 2018 |
| Priority date | — |
| Expiry date | Apr 27, 2035 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2800/52
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
An in vitro method for determining whether a patient has, or is at risk of having or developing an autoimmune disease or for assessing the severity or predicting the outcome of an autoimmune disease, comprising a step of detecting or quantifying in a biological sample obtained from said patient an immune anti-IL2 response, peptides specifically recognized by anti-IL2 antibodies or IL-2-specific T cells of T1D, systemic lupus erythematosus, rheumatoid arthritis, Sjögren's syndrome and autoimmune polymyositis patients, and pharmaceutical compositions.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.