Systems pharmacology for treating ocular disorders
US10117868B2 · kind B2 · utility
6Cited by
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17Claims
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Key dates
| Filing date | Apr 14, 2017 |
| Grant date | Nov 6, 2018 |
| Priority date | — |
| Expiry date | Apr 14, 2037 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K45/06
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A method of treating an ocular disorder in a subject includes administering to the subject subtherapeutic amounts of two or more agents that inhibit and/or blocks the activation of Gs- or Gq-protein coupled receptors or Gs- or Gq-signaling cascade in ocular cells of the subject, and/or activates Gi-protein coupled receptors, which is induced or triggered by light induced all-trans-retinal generation.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.