Non-fouling, anti-microbial, anti-thrombogenic graft-from compositions
US10117974B2 · kind B2 · utility
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33References
14Claims
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Key dates
| Filing date | Nov 3, 2014 |
| Grant date | Nov 6, 2018 |
| Priority date | — |
| Expiry date | Aug 27, 2036 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10T442/60
- WIPO fieldMacromolecular chemistry, polymers
- WIPO sectorChemistry
Abstract
A method for preparing and resulting articles of manufacture comprising a substrate having a surface, a bulk beneath the surface, and a grafted polymer layer on the substrate surface, the substrate surface and the grafted polymer layer, in combination, constituting a modified surface having a fibrinogen adsorption of less than about 125 ng/cm2 in a fibrinogen binding assay in which the modified surface is incubated for 60 minutes at 37° C. in 70 μg/mL fibrinogen derived from human plasma containing 1.4 μg/mL I-125 radiolabeled fibrinogen.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.