Aminotriazole-based KDM1A inhibitors as epigenetic modulators
US10118903B2 · kind B2 · utility
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18Claims
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Key dates
| Filing date | Feb 6, 2015 |
| Grant date | Nov 6, 2018 |
| Priority date | — |
| Expiry date | Feb 6, 2035 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D405/12
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
In some aspects, the present invention provides compounds of the formula (IV), wherein the variables are as defined herein, which may be used as inhibitors of histone demethylase or spermine oxidase. Also provided herein are pharmaceutical compositions of the compounds and methods using the compounds in the treatment of diseases such as cancer and cardiovascular disease.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.