Patent · US Active

Glucocorticoid-induced tumor necrosis factor receptor ligand (GITRL) single-chain fusion polypeptides

US10118953B2 · kind B2 · utility

1Cited by

2References

13Claims

0Family size

Assignee

APOGENIX AG · DE

Inventors

Oliver Hill · Neckarsteinach, DE
Christian Gieffers · Dossenheim, DE
Meinolf Thiemann · Schriesheim, DE

Key dates

Filing date	Jul 7, 2017
Grant date	Nov 6, 2018
Priority date	—
Expiry date	Jul 7, 2037

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07K2319/74
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention refers to single-chain fusion proteins comprising three soluble TNF superfamily (TNFSF) cytokine domains and nucleic acid molecules encoding these fusion proteins. The fusion proteins are substantially non-aggregating and suitable for therapeutic, diagnostic and/or research applications.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.