Patent · US Active

Human plasma kallikrein inhibitors

US10125102B2 · kind B2 · utility

15Cited by
2References
16Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMar 9, 2015
Grant dateNov 13, 2018
Priority date
Expiry dateMar 9, 2035

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D417/12
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Disclosed are compounds of formula Ias described herein, and pharmaceutically acceptable salts thereof. The compounds are inhibitors of plasma kallikrein. Also disclosed are pharmaceutical compositions comprising at least one such compound, and methods involving use of the compounds and compositions in the treatment and prevention of diseases and conditions characterized by unwanted plasma kallikrein activity.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.