Method to produce a highly concentrated immunoglobulin preparation for subcutaneous use

US10125189B2 · kind B2 · utility

Assignee

• Baxalta Incorporated · CH

Inventors

• Wolfgang Teschner · Wien, AT
• Harald Arno Butterweck · Wien, AT
• Azra Pljevljakovic · Wien, AT
• Theresa Friederike Bauer · Wien, AT
• Bernhard Koelbl · Achau, AT
• Hans-Peter Schwarz · Wien, AT
• Nebojsa Nikolic · Wien, AT
• Gerhard Poelsler · Wien, AT
• Johanna Kindermann · Mödling, AT

Key dates

• Filing date: Sep 16, 2015
• Grant date: Nov 13, 2018
• Expiry date: May 19, 2036

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07K2317/21
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention relates to a new and improved method for preparing a highly concentrated immunoglobulin composition from pooled plasma for subcutaneous injection. A composition comprising 20% or more immunoglobulin suitable for subcutaneous use is also described.