Amino acid preparation method comprising a step of hydroformylation of an unsaturated fatty nitrile
US10125221B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Dec 3, 2012 |
| Grant date | Nov 13, 2018 |
| Priority date | — |
| Expiry date | Dec 3, 2032 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C253/30
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A process for synthesizing an ω-amino acid compound of formula HOOC—(CH2)r+2—CH2NH2, wherein 4≤r≤13 from a monounsaturated fatty nitrile compound of formula CH2═CH—(CH2)r—CN the process comprising: 1) a step of hydroformylation of the mono unsaturated fatty nitrile compound by reacting said nitrile with carbon monoxide and di hydrogen 5e-a5 to obtain a nitrile aldehyde compound of formula HOC—(CH2)r+2-CN, then 2) a step of oxidation, in the presence of dioxygen, of the nitrile aldehyde compound to obtain a corresponding nitrile acid compound of formula HOOC—(CH2)r+2-CN, and 3) a step of reduction of the nitrile acid compound to give an w-amino acid of formula HOOC—(CH2)r+2—CH2NH2.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.