Systems for optical imaging of biological tissues
US10130259B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Feb 5, 2015 |
| Grant date | Nov 20, 2018 |
| Priority date | — |
| Expiry date | Nov 13, 2035 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG02B6/3624
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A fiber-based polarization sensitive optical coherence tomography (PS-OCT) system uses a new polarization diversity detection (PDD) scheme and requires no active polarization modulating components. Retardation of the sample can be determined from amplitudes of arbitrarily-oriented x- and y-components of the reflected light. A hybrid custom 50/50 coupler with single-mode fiber inputs and polarization maintaining (PM) fiber outputs combines light from sample and reference arms of an interferometer. Another embodiment provides a system adapted to provide co-registered autofluorescence-optical coherence tomography (AF-OCT) imaging. AF excitation light is introduced and collected AF light is extracted at a fiber optic rotary joint (FORJ) equipped with an embedded dichroic mirror. A probe tip that uses a clad fiber to supply light to a focusing element provides enhanced OCT and AF performance.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.