Functionalised silicon nanoparticles

US10130588B2 · kind B2 · utility

Assignee

• WESTFÄLISCHE WILHELMS-UNIVERSITÄT MÜNSTER · DE

Inventors

• Holger Stephan · Stuttgart, DE
• Ralf Bergmann · Dresden, DE
• Alexander Ruffani · Heidenau, DE
• Luisa DeCola · Strasbourg, FR

Key dates

• Filing date: Dec 12, 2012
• Grant date: Nov 20, 2018
• Expiry date: Dec 12, 2032

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y10T428/2982
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention is related to silicon nanoparticles, a pharmaceutical composition comprising silicon nanoparticles, a method for synthesis of the silicon nanoparticles and their use for in vivo diagnostics, visualization of drug delivery or staining of cells, biological processes or pathways. The silicon nanoparticles are characterized that they comprise a silicon core of a size of 1 to 10 nm and are terminated with allylamine or poly(allylamine) comprising up to 10 allylamine groups.