Synergistic enhancement of the delivery of nucleic acids via blended formulations
US10130649B2 · kind B2 · utility
9Cited by
71References
14Claims
0Family size
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Key dates
| Filing date | Mar 14, 2014 |
| Grant date | Nov 20, 2018 |
| Priority date | — |
| Expiry date | Mar 14, 2034 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N33/543
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Disclosed herein are pharmaceutical compositions that comprise “blends” of lipid nanoparticles and related methods of using such blended compositions to deliver polynucleotides to one or more target cells, tissues or organs. The blended compositions are generally characterized as being able to efficiently deliver polynucleotides to target cells and by their ability to enhance the expression of such polynucleotides and the production of functional proteins by target cells.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.