Processes for production of tumor infiltrating lymphocytes and uses of same in immunotherapy
US10130659B2 · kind B2 · utility
35Cited by
13References
29Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Feb 8, 2018 |
| Grant date | Nov 20, 2018 |
| Priority date | — |
| Expiry date | Feb 8, 2038 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2506/30
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides improved and/or shortened methods for expanding TILs and producing therapeutic populations of TILs, including novel methods for expanding TIL populations in a closed system that lead to improved efficacy, improved phenotype, and increased metabolic health of the TILs in a shorter time period, while allowing for reduced microbial contamination as well as decreased costs. Such TILs find use in therapeutic treatment regimens.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.