Systems and methods for improved delivery of osteoinductive molecules in bone repair
US10130678B2 · kind B2 · utility
1Cited by
128References
12Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Dec 29, 2015 |
| Grant date | Nov 20, 2018 |
| Priority date | — |
| Expiry date | Jan 10, 2036 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61L2430/38
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Systems and methods for preparing synthetic osteoinductive bone grafts are provided in which a porous ceramic granule, which may be incorporated within a biocompatible matrix material, is loaded with an osteoinductive agent. Loading of granules is facilitated in some cases by the use of low-pH buffers and pre-treatments.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.