Patent · US Active

System for detecting rare cells

US10130946B2 · kind B2 · utility

1Cited by

10References

28Claims

0Family size

Assignee

THE REGENTS OF THE UNIVERSITY OF MICHIGAN · US

Inventors

Sunitha Nagrath · Ann Arbor, US
Vasudha Murlidhar · Ann Arbor, US

Key dates

Filing date	Apr 6, 2015
Grant date	Nov 20, 2018
Priority date	—
Expiry date	Mar 20, 2036

Classification

Technology area (CPC B)Performing Operations; Transporting
CPC primaryB01L2400/088
WIPO fieldMeasurement
WIPO sectorInstruments

Abstract

This disclosure provides a system for detecting rare cells. The system includes a substrate, extensions extending outwardly from the substrate and arranged about a center axis of the substrate to define a channel enabling the fluid to move radially from the center axis to an outer edge of the substrate, and a functionalized graphene oxide disposed on the extension. This disclosure also provides a method for detecting rare cells using the system of this disclosure. The method includes the steps of introducing a sample of fluid containing the rare cells into the inlet of the system such that the sample of fluid flows radially from the inlet toward the outer edge of the substrate and capturing the rare cells as the rare cells interact with the functionalized graphene oxide disposed on the extensions.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.