TH-302 solid forms and methods related thereto
US10131683B2 · kind B2 · utility
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2References
16Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jul 15, 2015 |
| Grant date | Nov 20, 2018 |
| Priority date | — |
| Expiry date | Jul 15, 2035 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07B2200/13
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides a new method for making TH-302 and solid forms thereof. The compound in its solid form is an effective anti-cancer agent and may be used in various pharmaceutical compositions, and are particularly effective for the treatment of cancer. The invention also provides a method for preparing such compounds and forms and for treating cancer in a mammal comprising the step of administering a therapeutically effective amount of a solid form of TH-302 thereof.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.