Noninvasive detection of fetal aneuploidy in egg donor pregnancies
US10131947B2 · kind B2 · utility
2Cited by
121References
19Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Dec 19, 2012 |
| Grant date | Nov 20, 2018 |
| Priority date | — |
| Expiry date | Dec 13, 2035 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG16B30/00
- WIPO fieldComputer technology
- WIPO sectorElectrical engineering
Abstract
The present invention provides assay systems and methods for determining the percent fetal contribution of cell-free DNA in a maternal sample from a pregnant female with an egg donor pregnancy. Further provided, are assay systems and methods for determining a statistical likelihood of the presence or absence of a fetal aneuploidy in a maternal sample using a determined percent fetal cell-free DNA in the sample.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.